Hydrogen iodide-promoted reduction of β-chlorovinamidinium salts

Ian W. Davies, Mark Taylor, David Hughes, Paul J. Reider

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


(matrix presented) HI cleanly reduced chlorovinamidinium salts to the vinamidinium salt in essentially quantitative assay yield and 55-85% isolated yield following recrystallization. The reaction proceeds via protonation of the β-carbon atom of the vinamidinium and dechlorination via the formation of I-CI.

Original languageEnglish (US)
Pages (from-to)3385-3387
Number of pages3
JournalOrganic letters
Issue number21
StatePublished - Oct 19 2000
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry


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