Hydrodynamic trap for single particles and cells

Melikhan Tanyeri; Eric M. Johnson-Chavarria; Charles M. Schroeder

doi:10.1063/1.3431664

Hydrodynamic trap for single particles and cells

Melikhan Tanyeri
, Eric M. Johnson-Chavarria
, Charles M. Schroeder

Research output: Contribution to journal › Article › peer-review

126 Scopus citations

Abstract

Trapping and manipulation of microscale and nanoscale particles is demonstrated using the sole action of hydrodynamic forces. We developed an automated particle trap based on a stagnation point flow generated in a microfluidic device. The hydrodynamic trap enables confinement and manipulation of single particles in low viscosity (1-10 cP) aqueous solution. Using this method, we trapped microscale and nanoscale particles (100 nm-15 μm) for long time scales (minutes to hours). We demonstrate particle confinement to within 1 μm of the trap center, corresponding to a trap stiffness of ∼ 10 ^-5 - 10^-4 pN/nm.

Original language	English (US)
Article number	224101
Journal	Applied Physics Letters
Volume	96
Issue number	22
DOIs	https://doi.org/10.1063/1.3431664
State	Published - May 31 2010
Externally published	Yes

All Science Journal Classification (ASJC) codes

Physics and Astronomy (miscellaneous)

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10.1063/1.3431664

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title = "Hydrodynamic trap for single particles and cells",

abstract = "Trapping and manipulation of microscale and nanoscale particles is demonstrated using the sole action of hydrodynamic forces. We developed an automated particle trap based on a stagnation point flow generated in a microfluidic device. The hydrodynamic trap enables confinement and manipulation of single particles in low viscosity (1-10 cP) aqueous solution. Using this method, we trapped microscale and nanoscale particles (100 nm-15 μm) for long time scales (minutes to hours). We demonstrate particle confinement to within 1 μm of the trap center, corresponding to a trap stiffness of ∼ 10 -5 - 10-4 pN/nm.",

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AU - Tanyeri, Melikhan

AU - Johnson-Chavarria, Eric M.

AU - Schroeder, Charles M.

PY - 2010/5/31

Y1 - 2010/5/31

N2 - Trapping and manipulation of microscale and nanoscale particles is demonstrated using the sole action of hydrodynamic forces. We developed an automated particle trap based on a stagnation point flow generated in a microfluidic device. The hydrodynamic trap enables confinement and manipulation of single particles in low viscosity (1-10 cP) aqueous solution. Using this method, we trapped microscale and nanoscale particles (100 nm-15 μm) for long time scales (minutes to hours). We demonstrate particle confinement to within 1 μm of the trap center, corresponding to a trap stiffness of ∼ 10 -5 - 10-4 pN/nm.

AB - Trapping and manipulation of microscale and nanoscale particles is demonstrated using the sole action of hydrodynamic forces. We developed an automated particle trap based on a stagnation point flow generated in a microfluidic device. The hydrodynamic trap enables confinement and manipulation of single particles in low viscosity (1-10 cP) aqueous solution. Using this method, we trapped microscale and nanoscale particles (100 nm-15 μm) for long time scales (minutes to hours). We demonstrate particle confinement to within 1 μm of the trap center, corresponding to a trap stiffness of ∼ 10 -5 - 10-4 pN/nm.

UR - https://www.scopus.com/pages/publications/77953586223

UR - https://www.scopus.com/pages/publications/77953586223#tab=citedBy

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VL - 96

JO - Applied Physics Letters

JF - Applied Physics Letters

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ER -

Hydrodynamic trap for single particles and cells

Abstract

All Science Journal Classification (ASJC) codes

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