Hydrodynamic interaction between overlapping domains during recurrence of registration within planar lipid bilayer membranes

Tao Han, Trevor P. Bailey, Mikko Haataja

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Due to a thermodynamic coupling between the two leaflets comprising a lipid bilayer, compositional lipid domains residing within opposing leaflets are often found in registry. If the system is perturbed by displacing one domain relative to the other, diffusive and advective lipid fluxes are established to restore equilibrium and reestablish domain overlap. In this work, we focus on the advective part of the process, and first derive an analytical expression for the hydrodynamic drag coefficient associated with the advective flow for the special case of perfect domain overlap. The resulting expression identifies parameter regions where sliding friction between the leaflets dominates over viscous dissipation within the leaflets or vice versa. It is shown that in all practically relevant cases, sliding friction between the leaflets is the dominant factor. Finally, we investigate the domain separation dependence of the hydrodynamic drag coefficient via direct simulations of a continuum diffuse interface model, and provide useful empirical expressions for its behavior.

Original languageEnglish (US)
Article number032717
JournalPhysical Review E - Statistical, Nonlinear, and Soft Matter Physics
Volume89
Issue number3
DOIs
StatePublished - Mar 26 2014

All Science Journal Classification (ASJC) codes

  • Statistical and Nonlinear Physics
  • Statistics and Probability
  • Condensed Matter Physics

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