Hybrid Physics-Informed Metabolic Cybergenetics: Process Rates Augmented with Machine-Learning Surrogates Informed by Flux Balance Analysis

Biochemistry, Genetics and Molecular Biology

• Cell Metabolism 50%
• Enzyme 50%
• Escherichia coli 50%
• Gene Expression 100%
• Metabolic Flux 50%
• Metabolic Network 100%
• Metabolic Regulation 50%
• Process Monitoring 50%
• Process Optimization 50%

Chemical Engineering

• Learning System 100%
• Process Monitoring 50%

Keyphrases

• Dynamic Metabolic Control 20%
• Intracellular Enzymes 20%
• Macrokinetic Model 20%