Human cytomegalovirus inhibits the growth of human foreskin fibroblast cells by 12 h after infection. Analysis of the cellular DNA content of infected cells by flow cytometry demonstrated thai cytomegalovirus does not arrest cell cycle progression at a single point. At least two blockages occur, one of which is in the G1 phase of the cell cycle. The G1 arrest introduced by cytomegalovirus infection blocks S-phase entry after serum stimulation.
|Original language||English (US)|
|Number of pages||8|
|Journal||Journal of virology|
|State||Published - Dec 1996|
All Science Journal Classification (ASJC) codes
- Insect Science