How does the end begin?. Formation and maintenance of telomeres in ciliates and yeast

Virginia A. Zakian, Kurt Runge, Sy Shi Wang

Research output: Contribution to journalArticle

37 Scopus citations

Abstract

Current models of telomere formation and replication involve either telomerase, a novel ribonucleoprotein, or recombination between the ends of DNA molecules. However, present models will have to be modified to explain recent data on telomere formation in yeast. An understanding of the mechanisms of telomere maintenance in yeast may reveal how other organisms with heterogeneous telomeric repeats replicate their chromosomal termini.

Original languageEnglish (US)
Pages (from-to)12-16
Number of pages5
JournalTrends in Genetics
Volume6
Issue numberC
DOIs
StatePublished - 1990

All Science Journal Classification (ASJC) codes

  • Genetics

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