Histone H1.2 as a trigger for apoptosis

Nieng Yan; Yigong Shi

doi:10.1038/nsb1203-983

Histone H1.2 as a trigger for apoptosis

Nieng Yan, Yigong Shi

Research output: Contribution to journal › Short survey › peer-review

19 Scopus citations

Abstract

In response to DNA double-strand breaks, histone H1.2 translocates from the nucleus into the cytoplasm, leading to the mitochondrial release of cytochrome c and subsequent apoptosis of the cell. The molecular underpinnings for these processes remain enigmatic.

Original language	English (US)
Pages (from-to)	983-985
Number of pages	3
Journal	Nature Structural Biology
Volume	10
Issue number	12
DOIs	https://doi.org/10.1038/nsb1203-983
State	Published - Dec 2003

All Science Journal Classification (ASJC) codes

Structural Biology
Biochemistry
Genetics

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title = "Histone H1.2 as a trigger for apoptosis",

abstract = "In response to DNA double-strand breaks, histone H1.2 translocates from the nucleus into the cytoplasm, leading to the mitochondrial release of cytochrome c and subsequent apoptosis of the cell. The molecular underpinnings for these processes remain enigmatic.",

author = "Nieng Yan and Yigong Shi",

year = "2003",

month = dec,

doi = "10.1038/nsb1203-983",

language = "English (US)",

volume = "10",

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journal = "Nature Structural Biology",

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T1 - Histone H1.2 as a trigger for apoptosis

AU - Yan, Nieng

AU - Shi, Yigong

PY - 2003/12

Y1 - 2003/12

N2 - In response to DNA double-strand breaks, histone H1.2 translocates from the nucleus into the cytoplasm, leading to the mitochondrial release of cytochrome c and subsequent apoptosis of the cell. The molecular underpinnings for these processes remain enigmatic.

AB - In response to DNA double-strand breaks, histone H1.2 translocates from the nucleus into the cytoplasm, leading to the mitochondrial release of cytochrome c and subsequent apoptosis of the cell. The molecular underpinnings for these processes remain enigmatic.

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U2 - 10.1038/nsb1203-983

DO - 10.1038/nsb1203-983

M3 - Short survey

C2 - 14634629

AN - SCOPUS:0345490962

SN - 1072-8368

VL - 10

SP - 983

EP - 985

JO - Nature Structural Biology

JF - Nature Structural Biology

IS - 12

ER -

Histone H1.2 as a trigger for apoptosis

Abstract

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