Highly diastereoselective diels-alder reaction mediated by a chiral auxiliary derived from amino indanol: The role of conformation on diastereoselectivity

Ian W. Davies, Chris H. Senanayake, Laurie Castonguay, Robert D. Larsen, Thomas R. Verhoeven, Paul J. Reider

Research output: Contribution to journalArticle

53 Scopus citations

Abstract

The oxazolidinone 2 derived from amino indanol 1 functions as a very efficient chiral auxiliary for the Diels-Alder reaction. The effect of conformation has been explored using a range of constrained phenyl glycinol analogues.

Original languageEnglish (US)
Pages (from-to)7619-7622
Number of pages4
JournalTetrahedron Letters
Volume36
Issue number42
DOIs
StatePublished - Oct 16 1995
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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