High-altitude pulmonary edema (HAPE)

Robert B. Schoene, Erik R. Swenson

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations


Much of the clinical impact of acute altitude illnesses stems from fluid accumulation in interstitial spaces and nowhere is this more apparent than in the lungs as the edema escapes into the alveoli to cause life-threatening hypoxemia. This chapter will update our knowledge of HAPE over the past decade about the vasculature, alveolar epithelium, innervation, immune response, and genetics of the lung in hypoxia, as well as prophylactic and therapeutic strategies to reduce the toll of this most common alpine life-threatening illness.

Original languageEnglish (US)
Title of host publicationHigh Altitude
Subtitle of host publicationHuman Adaptation to Hypoxia
PublisherSpringer New York
Number of pages23
ISBN (Electronic)9781461487722
ISBN (Print)1461487714, 9781461487715
StatePublished - Jul 1 2014
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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