Graphene based electrochemical sensors and biosensors: A review

Yuyan Shao, Jun Wang, Hong Wu, Jun Liu, Ilhan A. Aksay, Yuehe Lin

Research output: Contribution to journalReview articlepeer-review

2810 Scopus citations


Graphene, emerging as a true 2-dimensional material, has received increasing attention due to its unique physicochemical properties (high surface area, excellent conductivity, high mechanical strength, and ease of functionalization and mass production). This article selectively reviews recent advances in graphene-based electrochemical sensors and biosensors. In particular, graphene for direct electrochemistry of enzyme, its electrocatalytic activity toward small biomolecules (hydrogen peroxide, NADH, dopamine, etc.), and graphene-based enzyme biosensors have been summarized in more detail; Graphene-based DNA sensing and environmental analysis have been discussed. Future perspectives in this rapidly developing field are also discussed.

Original languageEnglish (US)
Pages (from-to)1027-1036
Number of pages10
Issue number10
StatePublished - May 2010

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Electrochemistry


  • Biosensors
  • Carbon nanotubes
  • DNA
  • Direct electrochemistry
  • Enzyme
  • Glucose
  • Graphene


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