Getting RNA and protein in phase

Stephanie C. Weber; Clifford P. Brangwynne

doi:10.1016/j.cell.2012.05.022

Getting RNA and protein in phase

Stephanie C. Weber, Clifford P. Brangwynne

Research output: Contribution to journal › Review article › peer-review

358 Scopus citations

Abstract

Nonmembrane-bound organelles such as RNA granules behave like dynamic droplets, but the molecular details of their assembly are poorly understood. Several recent papers identify structural features that drive granule assembly, shedding light on how phase transitions functionally organize the cell and may lead to pathological protein aggregation.

Original language	English (US)
Pages (from-to)	1188-1191
Number of pages	4
Journal	Cell
Volume	149
Issue number	6
DOIs	https://doi.org/10.1016/j.cell.2012.05.022
State	Published - Jun 8 2012

All Science Journal Classification (ASJC) codes

Biochemistry, Genetics and Molecular Biology(all)

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10.1016/j.cell.2012.05.022

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title = "Getting RNA and protein in phase",

abstract = "Nonmembrane-bound organelles such as RNA granules behave like dynamic droplets, but the molecular details of their assembly are poorly understood. Several recent papers identify structural features that drive granule assembly, shedding light on how phase transitions functionally organize the cell and may lead to pathological protein aggregation.",

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AU - Weber, Stephanie C.

AU - Brangwynne, Clifford P.

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DO - 10.1016/j.cell.2012.05.022

M3 - Review article

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VL - 149

SP - 1188

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JO - Cell

JF - Cell

IS - 6

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Getting RNA and protein in phase

Abstract

All Science Journal Classification (ASJC) codes

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