TY - JOUR
T1 - Germline autonomy of maternal-effect mutations altering the embryonic body pattern of Drosophila
AU - Schupbach, Trudi
AU - Wieschaus, Eric
N1 - Funding Information:
For discussion and encouragement, we thank Dr, Ch. Ntisslein-Vol-hard and Dr. R. Nothiger. This research was supported by United States Public Health Service Grant 5ROl HD15587 to Eric Wieschaus, by Swiss National Science Foundation Grant 3.460.79 to R. Nothiger, and by a postdoctoral fellowship from the Swiss National Science Foundation.
PY - 1986/2
Y1 - 1986/2
N2 - Nine maternal-effect loci of Drosophila melanogaster were tested in germline mosaics to determine whether the wildtype gene activity is required in somatic or germline components of the maternal ovary. Mutations in these loci affect the anterior-posterior or dorso-ventral body pattern. In all nine loci (torso, trunk, exuperantia, vasa, valois, staufen, tudor, dorsal, Toll) a mutant genotype in the germ cells is sufficient to produce all aspects of the mutant embryonic phenotype, even when those germ cells are surrounded by wildtype somatic tissues.
AB - Nine maternal-effect loci of Drosophila melanogaster were tested in germline mosaics to determine whether the wildtype gene activity is required in somatic or germline components of the maternal ovary. Mutations in these loci affect the anterior-posterior or dorso-ventral body pattern. In all nine loci (torso, trunk, exuperantia, vasa, valois, staufen, tudor, dorsal, Toll) a mutant genotype in the germ cells is sufficient to produce all aspects of the mutant embryonic phenotype, even when those germ cells are surrounded by wildtype somatic tissues.
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U2 - 10.1016/0012-1606(86)90179-X
DO - 10.1016/0012-1606(86)90179-X
M3 - Article
C2 - 3081391
AN - SCOPUS:0022508110
SN - 0012-1606
VL - 113
SP - 443
EP - 448
JO - Developmental biology
JF - Developmental biology
IS - 2
ER -