Germline autonomy of maternal-effect mutations altering the embryonic body pattern of Drosophila

Trudi Schupbach, Eric Wieschaus

Research output: Contribution to journalArticle

160 Scopus citations

Abstract

Nine maternal-effect loci of Drosophila melanogaster were tested in germline mosaics to determine whether the wildtype gene activity is required in somatic or germline components of the maternal ovary. Mutations in these loci affect the anterior-posterior or dorso-ventral body pattern. In all nine loci (torso, trunk, exuperantia, vasa, valois, staufen, tudor, dorsal, Toll) a mutant genotype in the germ cells is sufficient to produce all aspects of the mutant embryonic phenotype, even when those germ cells are surrounded by wildtype somatic tissues.

Original languageEnglish (US)
Pages (from-to)443-448
Number of pages6
JournalDevelopmental biology
Volume113
Issue number2
DOIs
StatePublished - Feb 1986

All Science Journal Classification (ASJC) codes

  • Molecular Biology
  • Developmental Biology
  • Cell Biology

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