Germ-line dependence of the maroon-like maternal effect in Drosophila

J. L. Marsh, E. Wieschaus

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17 Scopus citations


We have used pole cell transplantations to construct germ-line mosaics for maroon-like (mal), a maternal effect mutation in Drosophila. Such mosaics allow one to determine the cell type in which a gene is active. We find that the maroon-like maternal effect is (1) autonomous to the germ line and (2) dose sensitive in germ-line mosaics. Aldehyde oxidase activity is used as a histological probe to investigate the tissue and temporal distribution of mal+ activity in the developing ovary. The adult ovary shows mal+ activity in the germ line at all discernible stages of oogenesis but no activity is observed in the mesodermally derived follicle cells. Differential mal+ activity is observed even in the ovary of the third-instar larvae.

Original languageEnglish (US)
Pages (from-to)396-403
Number of pages8
JournalDevelopmental biology
Issue number2
StatePublished - Oct 15 1977

All Science Journal Classification (ASJC) codes

  • Molecular Biology
  • Cell Biology
  • Developmental Biology


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