Genome Sequencing Fishes out Longevity Genes

Vanisha Lakhina; Coleen T. Murphy

doi:10.1016/j.cell.2015.11.040

Genome Sequencing Fishes out Longevity Genes

Vanisha Lakhina, Coleen T. Murphy

Research output: Contribution to journal › Short survey › peer-review

5 Scopus citations

Abstract

Understanding the molecular basis underlying aging is critical if we are to fully understand how and why we age - and possibly how to delay the aging process. Up until now, most longevity pathways were discovered in invertebrates because of their short lifespans and availability of genetic tools. Now, Reichwald et al. and Valenzano et al. independently provide a reference genome for the short-lived African turquoise killifish, establishing its role as a vertebrate system for aging research.

Original language	English (US)
Pages (from-to)	1312-1313
Number of pages	2
Journal	Cell
Volume	163
Issue number	6
DOIs	https://doi.org/10.1016/j.cell.2015.11.040
State	Published - Dec 3 2015

All Science Journal Classification (ASJC) codes

General Biochemistry, Genetics and Molecular Biology

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10.1016/j.cell.2015.11.040

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abstract = "Understanding the molecular basis underlying aging is critical if we are to fully understand how and why we age - and possibly how to delay the aging process. Up until now, most longevity pathways were discovered in invertebrates because of their short lifespans and availability of genetic tools. Now, Reichwald et al. and Valenzano et al. independently provide a reference genome for the short-lived African turquoise killifish, establishing its role as a vertebrate system for aging research.",

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AU - Murphy, Coleen T.

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AB - Understanding the molecular basis underlying aging is critical if we are to fully understand how and why we age - and possibly how to delay the aging process. Up until now, most longevity pathways were discovered in invertebrates because of their short lifespans and availability of genetic tools. Now, Reichwald et al. and Valenzano et al. independently provide a reference genome for the short-lived African turquoise killifish, establishing its role as a vertebrate system for aging research.

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JO - Cell

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Genome Sequencing Fishes out Longevity Genes

Abstract

All Science Journal Classification (ASJC) codes

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