Genome sequence of the virulent model herpes simplex virus 1 strain McKrae demonstrates the presence of at least two widely used variant strains

Daniel W. Renner; Lance Parsons; Jacob T. Shreve; Esteban A. Engel; Chad V. Kuny; Lynn Enquist; Donna Neumann; Colleen Mangold; Moriah L. Szpara

doi:10.1128/MRA.01146-19

Genome sequence of the virulent model herpes simplex virus 1 strain McKrae demonstrates the presence of at least two widely used variant strains

Daniel W. Renner, Lance Parsons, Jacob T. Shreve, Esteban A. Engel, Chad V. Kuny, Lynn Enquist, Donna Neumann, Colleen Mangold, Moriah L. Szpara

Princeton Neuroscience Institute

Research output: Contribution to journal › Article › peer-review

Abstract

Herpes simplex virus 1 (HSV-1) strain McKrae was isolated in 1965 and has been utilized by many laboratories. Three HSV-1 strain McKrae stocks have been sequenced previously, revealing discrepancies in key genes. We sequenced the genome of HSV-1 strain McKrae from the laboratory of James M. Hill to better understand the genetic differences between isolates.

Original language	English (US)
Article number	e01146-19
Journal	Microbiology Resource Announcements
Volume	10
Issue number	12
DOIs	https://doi.org/10.1128/MRA.01146-19
State	Published - Mar 25 2021

All Science Journal Classification (ASJC) codes

Immunology and Microbiology (miscellaneous)
Genetics
Molecular Biology

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10.1128/MRA.01146-19

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Renner, D. W., Parsons, L., Shreve, J. T., Engel, E. A., Kuny, C. V., Enquist, L., Neumann, D., Mangold, C., & Szpara, M. L. (2021). Genome sequence of the virulent model herpes simplex virus 1 strain McKrae demonstrates the presence of at least two widely used variant strains. Microbiology Resource Announcements, 10(12), Article e01146-19. https://doi.org/10.1128/MRA.01146-19

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abstract = "Herpes simplex virus 1 (HSV-1) strain McKrae was isolated in 1965 and has been utilized by many laboratories. Three HSV-1 strain McKrae stocks have been sequenced previously, revealing discrepancies in key genes. We sequenced the genome of HSV-1 strain McKrae from the laboratory of James M. Hill to better understand the genetic differences between isolates.",

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AU - Engel, Esteban A.

AU - Kuny, Chad V.

AU - Enquist, Lynn

AU - Neumann, Donna

AU - Mangold, Colleen

AU - Szpara, Moriah L.

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AB - Herpes simplex virus 1 (HSV-1) strain McKrae was isolated in 1965 and has been utilized by many laboratories. Three HSV-1 strain McKrae stocks have been sequenced previously, revealing discrepancies in key genes. We sequenced the genome of HSV-1 strain McKrae from the laboratory of James M. Hill to better understand the genetic differences between isolates.

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Genome sequence of the virulent model herpes simplex virus 1 strain McKrae demonstrates the presence of at least two widely used variant strains

Abstract

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