Genome-Directed Lead Discovery: Biosynthesis, Structure Elucidation, and Biological Evaluation of Two Families of Polyene Macrolactams against Trypanosoma brucei

Pharmacology, Toxicology and Pharmaceutical Science

• Trypanosoma Brucei 100%
• Polyene 100%
• Structure Elucidation 100%
• Neglected Disease 50%
• Actinosynnema 50%
• African Trypanosomiasis 50%
• Micromonospora 50%
• Antitrypanosomal 50%
• Lead Compound 50%

Keyphrases

• Lead Discovery 100%
• Polyene Macrolactam 100%
• Structure Elucidation 100%
• Human African Trypanosomiasis 50%
• Actinosynnema Mirum 50%
• Neglected Diseases 50%
• Marine Actinobacteria 50%
• Antitrypanosomal Activity 50%
• Micromonospora 50%

Immunology and Microbiology

• Micromonospora 50%
• Neglected Disease 50%
• Actinosynnema 50%