Genetic analysis of the ompB locus in Escherichia coli K-12

Michael N. Hall; Thomas J. Silhavy

doi:10.1016/0022-2836(81)90218-7

Genetic analysis of the ompB locus in Escherichia coli K-12

Michael N. Hall, Thomas J. Silhavy

Research output: Contribution to journal › Article › peer-review

170 Scopus citations

Abstract

Fine-structure mapping and complementation analysis of the ompB locus indicate that this locus is comprised of two genes, envZ and ompR. These genes are ordered on the chromosome as follows: aroB-envZ-ompR-asd. A model is proposed for the ompB-mediated regulation of the major outer membrane porin genes, ompF and ompC. According to this model, the ompR gene product is a bifunctional regulatory protein. The envZ gene product is an envelope protein that senses the cell's external environment.

Original language	English (US)
Pages (from-to)	1-15
Number of pages	15
Journal	Journal of Molecular Biology
Volume	151
Issue number	1
DOIs	https://doi.org/10.1016/0022-2836(81)90218-7
State	Published - Sep 5 1981
Externally published	Yes

All Science Journal Classification (ASJC) codes

Molecular Biology
Structural Biology

Access to Document

10.1016/0022-2836(81)90218-7

Cite this

@article{a6575dede96a4655bb7cb314f8b1fdaa,

title = "Genetic analysis of the ompB locus in Escherichia coli K-12",

abstract = "Fine-structure mapping and complementation analysis of the ompB locus indicate that this locus is comprised of two genes, envZ and ompR. These genes are ordered on the chromosome as follows: aroB-envZ-ompR-asd. A model is proposed for the ompB-mediated regulation of the major outer membrane porin genes, ompF and ompC. According to this model, the ompR gene product is a bifunctional regulatory protein. The envZ gene product is an envelope protein that senses the cell's external environment.",

author = "Hall, {Michael N.} and Silhavy, {Thomas J.}",

note = "Funding Information: We thank D. Jackson for assiduousa ssistancew ith fl-galactosidasea ssays,a nd P. Fritz and S. Lucas for their help in typing the manuscript.T his research was sponsored by the National Cancer Institute under contract no. NOl-CO-75380 wit{\textquoteright}h Litton Bionetics, Inc.",

year = "1981",

month = sep,

day = "5",

doi = "10.1016/0022-2836(81)90218-7",

language = "English (US)",

volume = "151",

pages = "1--15",

journal = "Journal of Molecular Biology",

issn = "0022-2836",

publisher = "Academic Press Inc.",

number = "1",

}

TY - JOUR

T1 - Genetic analysis of the ompB locus in Escherichia coli K-12

AU - Hall, Michael N.

AU - Silhavy, Thomas J.

N1 - Funding Information: We thank D. Jackson for assiduousa ssistancew ith fl-galactosidasea ssays,a nd P. Fritz and S. Lucas for their help in typing the manuscript.T his research was sponsored by the National Cancer Institute under contract no. NOl-CO-75380 wit’h Litton Bionetics, Inc.

PY - 1981/9/5

Y1 - 1981/9/5

N2 - Fine-structure mapping and complementation analysis of the ompB locus indicate that this locus is comprised of two genes, envZ and ompR. These genes are ordered on the chromosome as follows: aroB-envZ-ompR-asd. A model is proposed for the ompB-mediated regulation of the major outer membrane porin genes, ompF and ompC. According to this model, the ompR gene product is a bifunctional regulatory protein. The envZ gene product is an envelope protein that senses the cell's external environment.

AB - Fine-structure mapping and complementation analysis of the ompB locus indicate that this locus is comprised of two genes, envZ and ompR. These genes are ordered on the chromosome as follows: aroB-envZ-ompR-asd. A model is proposed for the ompB-mediated regulation of the major outer membrane porin genes, ompF and ompC. According to this model, the ompR gene product is a bifunctional regulatory protein. The envZ gene product is an envelope protein that senses the cell's external environment.

UR - http://www.scopus.com/inward/record.url?scp=0019781275&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0019781275&partnerID=8YFLogxK

U2 - 10.1016/0022-2836(81)90218-7

DO - 10.1016/0022-2836(81)90218-7

M3 - Article

C2 - 6799653

AN - SCOPUS:0019781275

SN - 0022-2836

VL - 151

SP - 1

EP - 15

JO - Journal of Molecular Biology

JF - Journal of Molecular Biology

IS - 1

ER -

Genetic analysis of the ompB locus in Escherichia coli K-12

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this