Generation of large-area tunable uniform electric fields in microfluidic arrays for rapid DNA separation

L. Richard Huang, Jonas O. Tegenfeldt, Jessica J. Kraeft, James Christopher Sturm, Robert Hamilton Austin, Edward C. Cox

Research output: Contribution to journalConference article

19 Scopus citations

Abstract

Control of electric fields over large areas is crucial for the accurate delivery and manipulation of biologically important molecules in microfluidic systems. In this paper we present a novel method for generating tunable uniform electric fields over large microfluidic arrays in two dimensions, and its application to a microfabricated device that separates genomic DNA. The device fractionates large DNA molecules over three orders of magnitude faster than conventional methods.

Original languageEnglish (US)
Pages (from-to)363-366
Number of pages4
JournalTechnical Digest - International Electron Devices Meeting
StatePublished - Dec 1 2001
EventIEEE International Electron Devices Meeting IEDM 2001 - Washington, DC, United States
Duration: Dec 2 2001Dec 5 2001

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Electrical and Electronic Engineering
  • Materials Chemistry

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