From neurotoxin to neurotrophin

Christian Mirescu; Elizabeth Gould

doi:10.1038/nn0904-899

From neurotoxin to neurotrophin

Christian Mirescu, Elizabeth Gould

Research output: Contribution to journal › Short survey › peer-review

2 Scopus citations

Abstract

Glucocorticoids are important for neuronal function, but their release in conjunction with a brain injury can intensity neuronal death, causing more harm than good. A new study shows that delivery of genes that have been modified to alter glucocorticoid signaling can block the toxic effects of the hormone in vitro and in vivo, converting what was once a neuron's worst enemy into its best friend.

Original language	English (US)
Pages (from-to)	899-900
Number of pages	2
Journal	Nature neuroscience
Volume	7
Issue number	9
DOIs	https://doi.org/10.1038/nn0904-899
State	Published - Sep 2004

All Science Journal Classification (ASJC) codes

General Neuroscience

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10.1038/nn0904-899

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abstract = "Glucocorticoids are important for neuronal function, but their release in conjunction with a brain injury can intensity neuronal death, causing more harm than good. A new study shows that delivery of genes that have been modified to alter glucocorticoid signaling can block the toxic effects of the hormone in vitro and in vivo, converting what was once a neuron's worst enemy into its best friend.",

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AB - Glucocorticoids are important for neuronal function, but their release in conjunction with a brain injury can intensity neuronal death, causing more harm than good. A new study shows that delivery of genes that have been modified to alter glucocorticoid signaling can block the toxic effects of the hormone in vitro and in vivo, converting what was once a neuron's worst enemy into its best friend.

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From neurotoxin to neurotrophin

Abstract

All Science Journal Classification (ASJC) codes

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