From breast to the brain: Unraveling the puzzle of metastasis organotropism

Guohong Hu, Yibin Kang, Xiao Fan Wang

Research output: Contribution to journalArticlepeer-review

23 Scopus citations


Metastatic colonization of different target organs is a highly selective process that depends on specialized properties of tumor cells. In a recent Nature paper, Massagué and colleagues built on their earlier success in functional genomic analysis of breast cancer metastasis to bone and lung and reported the identification of breast cancer brain metastasis genes, highlighting the importance of the stromal environment in the development of organ-specific metastasis.

Original languageEnglish (US)
Pages (from-to)3-5
Number of pages3
JournalJournal of Molecular Cell Biology
Issue number1
StatePublished - 2009

All Science Journal Classification (ASJC) codes

  • Genetics
  • Molecular Biology
  • Cell Biology


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