Formation of monodisperse bubbles in a microfluidic flow-focusing device

Piotr Garstecki; Irina Gitlin; Willow Diluzio; George M. Whitesides; Eugenia Kumacheva; Howard A. Stone

doi:10.1063/1.1796526

Formation of monodisperse bubbles in a microfluidic flow-focusing device

Piotr Garstecki, Irina Gitlin, Willow Diluzio, George M. Whitesides, Eugenia Kumacheva, Howard A. Stone

Research output: Contribution to journal › Article › peer-review

583 Scopus citations

Abstract

A method for generating monodisperse gaseous bubbles in a microfluidic flow-focusing device was presented. The method could generate bubbles in the range of diameters from 10 to 1000 μm. The volume of the bubbles, in the method, was found to scale with the flow rate and the viscosity of the liquid, and the pressure of the gas stream. The method was demonstrated to allow simultaneous, independent control of the size of the individual bubbles and volume fraction of the dispersed phase.

Original language	English (US)
Pages (from-to)	2649-2651
Number of pages	3
Journal	Applied Physics Letters
Volume	85
Issue number	13
DOIs	https://doi.org/10.1063/1.1796526
State	Published - Sep 27 2004

All Science Journal Classification (ASJC) codes

Physics and Astronomy (miscellaneous)

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10.1063/1.1796526

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title = "Formation of monodisperse bubbles in a microfluidic flow-focusing device",

abstract = "A method for generating monodisperse gaseous bubbles in a microfluidic flow-focusing device was presented. The method could generate bubbles in the range of diameters from 10 to 1000 μm. The volume of the bubbles, in the method, was found to scale with the flow rate and the viscosity of the liquid, and the pressure of the gas stream. The method was demonstrated to allow simultaneous, independent control of the size of the individual bubbles and volume fraction of the dispersed phase.",

author = "Piotr Garstecki and Irina Gitlin and Willow Diluzio and Whitesides, {George M.} and Eugenia Kumacheva and Stone, {Howard A.}",

note = "Funding Information: We thank the Harvard DEAS Microfluidics Discussion Group for helpful conversations and the Harvard MRSEC for the use of high-speed cameras. P.G. acknowledges a fellowship from the Foundation for Polish Science. I.G. thanks the NSF for a pre-doctoral fellowship. E.K. thanks CRC funding. H.A.S. thanks Unilever for support. This work was supported by the U.S. Department of Energy (DE-FG02-00ER45852).",

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T1 - Formation of monodisperse bubbles in a microfluidic flow-focusing device

AU - Garstecki, Piotr

AU - Gitlin, Irina

AU - Diluzio, Willow

AU - Whitesides, George M.

AU - Kumacheva, Eugenia

AU - Stone, Howard A.

N1 - Funding Information: We thank the Harvard DEAS Microfluidics Discussion Group for helpful conversations and the Harvard MRSEC for the use of high-speed cameras. P.G. acknowledges a fellowship from the Foundation for Polish Science. I.G. thanks the NSF for a pre-doctoral fellowship. E.K. thanks CRC funding. H.A.S. thanks Unilever for support. This work was supported by the U.S. Department of Energy (DE-FG02-00ER45852).

PY - 2004/9/27

Y1 - 2004/9/27

N2 - A method for generating monodisperse gaseous bubbles in a microfluidic flow-focusing device was presented. The method could generate bubbles in the range of diameters from 10 to 1000 μm. The volume of the bubbles, in the method, was found to scale with the flow rate and the viscosity of the liquid, and the pressure of the gas stream. The method was demonstrated to allow simultaneous, independent control of the size of the individual bubbles and volume fraction of the dispersed phase.

AB - A method for generating monodisperse gaseous bubbles in a microfluidic flow-focusing device was presented. The method could generate bubbles in the range of diameters from 10 to 1000 μm. The volume of the bubbles, in the method, was found to scale with the flow rate and the viscosity of the liquid, and the pressure of the gas stream. The method was demonstrated to allow simultaneous, independent control of the size of the individual bubbles and volume fraction of the dispersed phase.

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Formation of monodisperse bubbles in a microfluidic flow-focusing device

Abstract

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