Recent efforts examining forces during morphogenesis suggest a role for mechanical crosstalk between epithelium and mesenchyme in tissue patterning. Reporting in Science, Shyer etal. (2013) show that differences between the mechanical properties of the developing intestinal epithelium and surrounding smooth muscle fold the epithelium into villi via mucosal buckling.
All Science Journal Classification (ASJC) codes
- General Biochemistry, Genetics and Molecular Biology
- Molecular Biology
- Cell Biology
- Developmental Biology