Fluorescent probes for sensing and imaging biological hydrogen sulfide

Vivian S. Lin; Christopher J. Chang

doi:10.1016/j.cbpa.2012.07.014

Fluorescent probes for sensing and imaging biological hydrogen sulfide

Vivian S. Lin, Christopher J. Chang

Research output: Contribution to journal › Review article › peer-review

247 Scopus citations

Abstract

Hydrogen sulfide (H₂S) has long been recognized as a toxic molecule in biological systems. However, emerging studies now link controlled fluxes of this reactive sulfur species to cellular regulation and signaling events akin to other small molecule messengers, such as nitric oxide, hydrogen peroxide, and carbon monoxide. Progress in the development of fluorescent small-molecule indicators with high selectivity for hydrogen sulfide offers a promising approach for studying its production, trafficking, and downstream physiological and/or pathological effects.

Original language	English (US)
Pages (from-to)	595-601
Number of pages	7
Journal	Current Opinion in Chemical Biology
Volume	16
Issue number	5-6
DOIs	https://doi.org/10.1016/j.cbpa.2012.07.014
State	Published - Dec 2012
Externally published	Yes

All Science Journal Classification (ASJC) codes

Analytical Chemistry
Biochemistry

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10.1016/j.cbpa.2012.07.014

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title = "Fluorescent probes for sensing and imaging biological hydrogen sulfide",

abstract = "Hydrogen sulfide (H2S) has long been recognized as a toxic molecule in biological systems. However, emerging studies now link controlled fluxes of this reactive sulfur species to cellular regulation and signaling events akin to other small molecule messengers, such as nitric oxide, hydrogen peroxide, and carbon monoxide. Progress in the development of fluorescent small-molecule indicators with high selectivity for hydrogen sulfide offers a promising approach for studying its production, trafficking, and downstream physiological and/or pathological effects.",

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doi = "10.1016/j.cbpa.2012.07.014",

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AU - Chang, Christopher J.

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AB - Hydrogen sulfide (H2S) has long been recognized as a toxic molecule in biological systems. However, emerging studies now link controlled fluxes of this reactive sulfur species to cellular regulation and signaling events akin to other small molecule messengers, such as nitric oxide, hydrogen peroxide, and carbon monoxide. Progress in the development of fluorescent small-molecule indicators with high selectivity for hydrogen sulfide offers a promising approach for studying its production, trafficking, and downstream physiological and/or pathological effects.

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Fluorescent probes for sensing and imaging biological hydrogen sulfide

Abstract

All Science Journal Classification (ASJC) codes

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