Flashy science: Controlling neural function with light

Scott M. Thompson, Joseph P.Y. Kao, Richard H. Kramer, Kira E. Poskanzer, R. Angus Silver, David Digregorio, Samuel S.H. Wang

Research output: Contribution to journalArticlepeer-review

17 Scopus citations

Abstract

In conclusion, the data discussed here demonstrate that light is not merely a medium for passively visualizing structures and events but rather a tool to be used actively for manipulating those structures and events. The approaches described above represent enabling technology that has wide application in neurobiology. We are convinced that the introduction of this powerful new technology will invariably stimulate new, as well as new types of, experiments.

Original languageEnglish (US)
Pages (from-to)10358-10365
Number of pages8
JournalJournal of Neuroscience
Volume25
Issue number45
DOIs
StatePublished - Nov 9 2005

All Science Journal Classification (ASJC) codes

  • General Neuroscience

Keywords

  • Activity
  • Caged molecule
  • Glutamate uncaging
  • Photoinactivation
  • Photolysis
  • Photostimulation

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