Fibronectin fibrillogenesis: A paradigm for extracellular matrix assembly

Jean E. Schwarzbauer, Jan L. Sechler

Research output: Contribution to journalReview articlepeer-review

255 Scopus citations


Fibronectin matrix assembly is a regulated stepwise process. In the past year, analyses of fibronectin domains, integrin and cytoskeletal contributions, and fibril architecture have provided new insights into assembly mechanisms and matrix control of cell functions. Like fibronectin, laminin polymerization is cell-mediated. Thus a common pathway for extracellular matrix assembly is emerging.

Original languageEnglish (US)
Pages (from-to)622-627
Number of pages6
JournalCurrent Opinion in Cell Biology
Issue number5
StatePublished - Oct 1 1999

All Science Journal Classification (ASJC) codes

  • Cell Biology


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