TY - JOUR
T1 - FEF-controlled alpha delay activity precedes stimulus-induced gamma-band activity in visual cortex
AU - Popov, Tzvetan
AU - Kastner, Sabine
AU - Jensen, Ole
N1 - Publisher Copyright:
© 2017 the authors.
PY - 2017/4/12
Y1 - 2017/4/12
N2 - Recent findings in the visual system of nonhuman primates have demonstrated an important role of gamma-band activity (40 -100 Hz) in the feedforward flow of sensory information, whereas feedback control appears to be established dynamically by oscillations in the alpha (8 -13 Hz) and beta (13-18 Hz) bands (van Kerkoerle et al., 2014; Bastos et al., 2015). It is not clear, however, how alpha oscillations are controlled and how they interact with the flow of visual information mediated by gamma-band activity. Using noninvasive human MEG recordings in subjects performing a visuospatial attention task, we show that fluctuations in alpha power during a delay period in a spatial attention task preceded subsequent stimulus-driven gamma-band activity. Importantly, these interactions correlated with behavioral performance. Using Granger analysis, we further show that the right frontal-eye field (rFEF) exerted feedback control of the visual alpha oscillations. Our findings suggest that alpha oscillations controlled by the FEF route cortical information flow by modulating gamma-band activity.
AB - Recent findings in the visual system of nonhuman primates have demonstrated an important role of gamma-band activity (40 -100 Hz) in the feedforward flow of sensory information, whereas feedback control appears to be established dynamically by oscillations in the alpha (8 -13 Hz) and beta (13-18 Hz) bands (van Kerkoerle et al., 2014; Bastos et al., 2015). It is not clear, however, how alpha oscillations are controlled and how they interact with the flow of visual information mediated by gamma-band activity. Using noninvasive human MEG recordings in subjects performing a visuospatial attention task, we show that fluctuations in alpha power during a delay period in a spatial attention task preceded subsequent stimulus-driven gamma-band activity. Importantly, these interactions correlated with behavioral performance. Using Granger analysis, we further show that the right frontal-eye field (rFEF) exerted feedback control of the visual alpha oscillations. Our findings suggest that alpha oscillations controlled by the FEF route cortical information flow by modulating gamma-band activity.
KW - Alpha gamma oscillations
KW - Executive control
KW - Flanker task
KW - Functional connectivity
KW - Magnetoencephalography
KW - Prefrontal control
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U2 - 10.1523/JNEUROSCI.3015-16.2017
DO - 10.1523/JNEUROSCI.3015-16.2017
M3 - Article
C2 - 28314817
AN - SCOPUS:85018543225
SN - 0270-6474
VL - 37
SP - 4117
EP - 4127
JO - Journal of Neuroscience
JF - Journal of Neuroscience
IS - 15
ER -