Feeding the germline

Cheng Shi; Coleen T. Murphy

doi:10.1101/gad.276980.115

Feeding the germline

Cheng Shi, Coleen T. Murphy

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Nucleotides are required in order to replicate DNA in the developing germline. Here, Chi and colleagues (pp. 307–320) have used Caernohabditis elegans to identify a GLP-1-dependent checkpoint that senses food (bacterially)- supplied nucleotide levels, arresting reproductive development in the absence of sufficient nucleotide supplies.

Original language	English (US)
Pages (from-to)	249-250
Number of pages	2
Journal	Genes and Development
Volume	30
Issue number	3
DOIs	https://doi.org/10.1101/gad.276980.115
State	Published - Feb 1 2016

All Science Journal Classification (ASJC) codes

Genetics
Developmental Biology

Keywords

CRP
CytR
Gld-1
HT115
Nucleotide salvage pathway
Nutrient sensing

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10.1101/gad.276980.115

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title = "Feeding the germline",

abstract = "Nucleotides are required in order to replicate DNA in the developing germline. Here, Chi and colleagues (pp. 307–320) have used Caernohabditis elegans to identify a GLP-1-dependent checkpoint that senses food (bacterially)- supplied nucleotide levels, arresting reproductive development in the absence of sufficient nucleotide supplies.",

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AB - Nucleotides are required in order to replicate DNA in the developing germline. Here, Chi and colleagues (pp. 307–320) have used Caernohabditis elegans to identify a GLP-1-dependent checkpoint that senses food (bacterially)- supplied nucleotide levels, arresting reproductive development in the absence of sufficient nucleotide supplies.

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KW - Nutrient sensing

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Feeding the germline

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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