Fatherhood affects dendritic spines and vasopressin V1a receptors in the primate prefrontal cortex

Yevgenia Kozorovitskiy; Maria Hughes; Kim Lee; Elizabeth Gould

doi:10.1038/nn1753

Fatherhood affects dendritic spines and vasopressin V1a receptors in the primate prefrontal cortex

Yevgenia Kozorovitskiy, Maria Hughes, Kim Lee, Elizabeth Gould

Research output: Contribution to journal › Article › peer-review

133 Scopus citations

Abstract

Like human fathers, male marmosets help raise their young, yet the ways in which fatherhood influences the brain remain largely unknown. We show that first-time and experienced marmoset fathers have enhanced density of dendritic spines on pyramidal neurons in prefrontal cortex as compared to non-fathers. In parallel, the abundance of vasopressin V1a receptors and the proportion of V1a receptor-labeled dendritic spines increase.

Original language	English (US)
Pages (from-to)	1094-1095
Number of pages	2
Journal	Nature neuroscience
Volume	9
Issue number	9
DOIs	https://doi.org/10.1038/nn1753
State	Published - Sep 2006

All Science Journal Classification (ASJC) codes

General Neuroscience

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10.1038/nn1753

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title = "Fatherhood affects dendritic spines and vasopressin V1a receptors in the primate prefrontal cortex",

abstract = "Like human fathers, male marmosets help raise their young, yet the ways in which fatherhood influences the brain remain largely unknown. We show that first-time and experienced marmoset fathers have enhanced density of dendritic spines on pyramidal neurons in prefrontal cortex as compared to non-fathers. In parallel, the abundance of vasopressin V1a receptors and the proportion of V1a receptor-labeled dendritic spines increase.",

author = "Yevgenia Kozorovitskiy and Maria Hughes and Kim Lee and Elizabeth Gould",

note = "Funding Information: We thank C. Gross, A. Pavlic, B. Leuner, C. Mirescu, M. McBreen and J. Goodhouse for their help. This work was supported by the US National Institutes of Health and National Alliance for Research on Schizophrenia and Depression, the Mental Health Research Association (E.G.), and a National Research Service Award fellowship (Y.K).",

year = "2006",

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AU - Kozorovitskiy, Yevgenia

AU - Hughes, Maria

AU - Lee, Kim

AU - Gould, Elizabeth

N1 - Funding Information: We thank C. Gross, A. Pavlic, B. Leuner, C. Mirescu, M. McBreen and J. Goodhouse for their help. This work was supported by the US National Institutes of Health and National Alliance for Research on Schizophrenia and Depression, the Mental Health Research Association (E.G.), and a National Research Service Award fellowship (Y.K).

PY - 2006/9

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N2 - Like human fathers, male marmosets help raise their young, yet the ways in which fatherhood influences the brain remain largely unknown. We show that first-time and experienced marmoset fathers have enhanced density of dendritic spines on pyramidal neurons in prefrontal cortex as compared to non-fathers. In parallel, the abundance of vasopressin V1a receptors and the proportion of V1a receptor-labeled dendritic spines increase.

AB - Like human fathers, male marmosets help raise their young, yet the ways in which fatherhood influences the brain remain largely unknown. We show that first-time and experienced marmoset fathers have enhanced density of dendritic spines on pyramidal neurons in prefrontal cortex as compared to non-fathers. In parallel, the abundance of vasopressin V1a receptors and the proportion of V1a receptor-labeled dendritic spines increase.

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Fatherhood affects dendritic spines and vasopressin V1a receptors in the primate prefrontal cortex

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