Facilitation of masseter EMG and masseteric (jaw-closure) reflex by serotonin in behaving cats

L. E. Ribeiro-do-Valle; C. W. Metzler; B. L. Jacobs

doi:10.1016/0006-8993(91)91318-U

Facilitation of masseter EMG and masseteric (jaw-closure) reflex by serotonin in behaving cats

L. E. Ribeiro-do-Valle, C. W. Metzler, B. L. Jacobs

Psychology

Research output: Contribution to journal › Article › peer-review

54 Scopus citations

Abstract

The trigeminal motor nucleus (MoV) contains the somata of the motoneurons that control jaw position and jaw movements. This nucleus is of neurochemical interest because it recieves a dense serotonergic input. We examined the effects of application oof serotonin or fluoxetine, a serotonin reuptake blocker, into this nucleus on the spontaneous or reflex (jaw-closure) electrical activity of the masseter muscle in behaving cats. Serotonin produced a clearcut enhancement of both spontaneous and reflex activities. This action was attenuated by previous systemic injection of the serotonin receptor antagonist methysergide. The effect was mimicked to a certain extent by fluoxetine. These data provide evidence that the serotonergic input to MoV exerts a general facilitatory influence on masseter motoneurons activity.

Original language	English (US)
Pages (from-to)	197-204
Number of pages	8
Journal	Brain Research
Volume	550
Issue number	2
DOIs	https://doi.org/10.1016/0006-8993(91)91318-U
State	Published - Jun 7 1991

All Science Journal Classification (ASJC) codes

Clinical Neurology
Molecular Biology
General Neuroscience
Developmental Biology

Keywords

Jaw-closure reflex
Masseter electromyogram
Masseteric reflex
Mesencephalic trigeminal nucleus
Serotonin
Trigeminal motor nucleus

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10.1016/0006-8993(91)91318-U

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title = "Facilitation of masseter EMG and masseteric (jaw-closure) reflex by serotonin in behaving cats",

abstract = "The trigeminal motor nucleus (MoV) contains the somata of the motoneurons that control jaw position and jaw movements. This nucleus is of neurochemical interest because it recieves a dense serotonergic input. We examined the effects of application oof serotonin or fluoxetine, a serotonin reuptake blocker, into this nucleus on the spontaneous or reflex (jaw-closure) electrical activity of the masseter muscle in behaving cats. Serotonin produced a clearcut enhancement of both spontaneous and reflex activities. This action was attenuated by previous systemic injection of the serotonin receptor antagonist methysergide. The effect was mimicked to a certain extent by fluoxetine. These data provide evidence that the serotonergic input to MoV exerts a general facilitatory influence on masseter motoneurons activity.",

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AU - Ribeiro-do-Valle, L. E.

AU - Metzler, C. W.

AU - Jacobs, B. L.

PY - 1991/6/7

Y1 - 1991/6/7

N2 - The trigeminal motor nucleus (MoV) contains the somata of the motoneurons that control jaw position and jaw movements. This nucleus is of neurochemical interest because it recieves a dense serotonergic input. We examined the effects of application oof serotonin or fluoxetine, a serotonin reuptake blocker, into this nucleus on the spontaneous or reflex (jaw-closure) electrical activity of the masseter muscle in behaving cats. Serotonin produced a clearcut enhancement of both spontaneous and reflex activities. This action was attenuated by previous systemic injection of the serotonin receptor antagonist methysergide. The effect was mimicked to a certain extent by fluoxetine. These data provide evidence that the serotonergic input to MoV exerts a general facilitatory influence on masseter motoneurons activity.

AB - The trigeminal motor nucleus (MoV) contains the somata of the motoneurons that control jaw position and jaw movements. This nucleus is of neurochemical interest because it recieves a dense serotonergic input. We examined the effects of application oof serotonin or fluoxetine, a serotonin reuptake blocker, into this nucleus on the spontaneous or reflex (jaw-closure) electrical activity of the masseter muscle in behaving cats. Serotonin produced a clearcut enhancement of both spontaneous and reflex activities. This action was attenuated by previous systemic injection of the serotonin receptor antagonist methysergide. The effect was mimicked to a certain extent by fluoxetine. These data provide evidence that the serotonergic input to MoV exerts a general facilitatory influence on masseter motoneurons activity.

KW - Jaw-closure reflex

KW - Masseter electromyogram

KW - Masseteric reflex

KW - Mesencephalic trigeminal nucleus

KW - Serotonin

KW - Trigeminal motor nucleus

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Facilitation of masseter EMG and masseteric (jaw-closure) reflex by serotonin in behaving cats

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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