Abstract
We report fabrication and performances of a new immunoassay device, which integrates a novel nanoplasmonic sensor array inside a microfluidic channel. The new assay has demonstrated 106 fold detection limit enhancement of a model direct Protein A immunoassay over glass reference (from 2nM to 850 aM, i.e. 120 ng/ml to 50 fg/ml) and 6 fold of incubation time reduction (2 hours to 20 min) compared to conventional 96-well plate immunoassay.
Original language | English (US) |
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Title of host publication | Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012 |
Publisher | Chemical and Biological Microsystems Society |
Pages | 266-268 |
Number of pages | 3 |
ISBN (Print) | 9780979806452 |
State | Published - Jan 1 2012 |
Event | 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012 - Okinawa, Japan Duration: Oct 28 2012 → Nov 1 2012 |
Other
Other | 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012 |
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Country/Territory | Japan |
City | Okinawa |
Period | 10/28/12 → 11/1/12 |
All Science Journal Classification (ASJC) codes
- Chemical Engineering (miscellaneous)
- Bioengineering