Exploring and exploiting proteome organization during viral infection

Pierre M.Jean Beltran, Katelyn C. Cook, Ileana M. Cristea

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

Viral replication in eukaryotes is a process inherently organized in both space and time. Viral components target subcellular organelles to access host machineries required for replication and spread. Diverse viruses are known to alter organelle shape, composition, function, and dynamics as part of their replication cycles. Here, we highlight recent advances in microscopy and proteomic methods that have helped and will continue to help define mechanisms used by viruses to exploit host proteome organization.

Original languageEnglish (US)
Article numbere00268-17
JournalJournal of virology
Volume91
Issue number18
DOIs
StatePublished - Sep 1 2017

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Immunology
  • Insect Science
  • Virology

Keywords

  • Mass spectrometry
  • Microscopy
  • Organelle
  • Proteomics
  • Systems biology
  • Virus-host interactions

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