Abstract
Boronic acids, esters and borinic anhydrides are partners in Suzuki-Miyaura cross-coupling reactions with a variety of β-chlorovinamidinium salts to give the desired β-arylvinamidinium salts in up to 88% yield. Reduction is a competing reaction pathway. DFT calculations on the intermediate palladium complex reveal that the Pd-C interaction is predominantly of σ-symmetry and the metal based LUMO is mainly dz2 in character.
Original language | English (US) |
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Pages (from-to) | 5061-5066 |
Number of pages | 6 |
Journal | Tetrahedron |
Volume | 57 |
Issue number | 24 |
DOIs | |
State | Published - Jun 11 2001 |
Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Biochemistry
- Drug Discovery
- Organic Chemistry