TY - JOUR
T1 - Expeditions to the pole
T2 - RNA localization in Xenopus and Drosophila
AU - Gavis, Elizabeth R.
N1 - Funding Information:
The observed precipitation data were provided by the China Meteorological Administration (http://www.escience.gov.cn/metdata/page/index.html). We appreciate the free access of the NASA's Land Data Assimilation Systems (http://ldas.gsfc.nasa.gov/gldas/). This research was supported by the Natural Science Foundation of China (41330529, 41571024, and 41201034) and the program for ?Bingwei? Excellent Talents, Institute of Geographic Sciences and Natural Resources Research, CAS (project 2013RC202).
PY - 1997/12
Y1 - 1997/12
N2 - In Xenopus ann Drosophila oocytes, a number of maternally synthesized RNAs encoding molecules that act in formation and patterning of embryonic tissues are localized to the vegetal and posterior poles, respectively. In Drosophila, and probably in Xenopus, localization of their RNAs within the oocyte generates the regionalized distributions of these molecules in the early embryo that are required for proper development. Studies described here have begun to reveal components of the cellular machinery that effects RNA localization. While specific aspects of localization differ among RNAs, similarities between pathways used by Xenopus and Drosophila suggest that common themes have been conserved among localization mechanisms.
AB - In Xenopus ann Drosophila oocytes, a number of maternally synthesized RNAs encoding molecules that act in formation and patterning of embryonic tissues are localized to the vegetal and posterior poles, respectively. In Drosophila, and probably in Xenopus, localization of their RNAs within the oocyte generates the regionalized distributions of these molecules in the early embryo that are required for proper development. Studies described here have begun to reveal components of the cellular machinery that effects RNA localization. While specific aspects of localization differ among RNAs, similarities between pathways used by Xenopus and Drosophila suggest that common themes have been conserved among localization mechanisms.
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U2 - 10.1016/S0962-8924(97)01162-8
DO - 10.1016/S0962-8924(97)01162-8
M3 - Review article
C2 - 17709012
AN - SCOPUS:0030690268
SN - 0962-8924
VL - 7
SP - 485
EP - 492
JO - Trends in Cell Biology
JF - Trends in Cell Biology
IS - 12
ER -