Everything you ever wanted to know about Saccharomyces cerevisiae telomeres: Beginning to end

Raymund J. Wellinger, Virginia A. Zakian

Research output: Contribution to journalReview articlepeer-review

182 Scopus citations

Abstract

The mechanisms that maintain the stability of chromosome ends have broad impact on genome integrity in all eukaryotes. Budding yeast is a premier organism for telomere studies. Many fundamental concepts of telomere and telomerase function were first established in yeast and then extended to other organisms. We present a comprehensive review of yeast telomere biology that covers capping, replication, recombination, and transcription. We think of it as yeast telomeres-soup to nuts.

Original languageEnglish (US)
Pages (from-to)1073-1105
Number of pages33
JournalGenetics
Volume191
Issue number4
DOIs
StatePublished - Aug 1 2012

All Science Journal Classification (ASJC) codes

  • Genetics

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