Abstract
Herein we disclose a deoxyfluorination of alcohols with an electrophilic fluorine source via visible-light photoredox catalysis. This radical-mediated C–F coupling is capable of fluorinating secondary and tertiary alcohols efficiently, complementing previously reported nucleophilic deoxyfluorination protocols.
| Original language | English (US) |
|---|---|
| Article number | 133494 |
| Journal | Tetrahedron |
| Volume | 141 |
| DOIs |
|
| State | Published - Jul 17 2023 |
All Science Journal Classification (ASJC) codes
- Biochemistry
- Drug Discovery
- Organic Chemistry
Keywords
- Deoxyfluorination
- Fluoroalkanes
- Oxalates
- Photoredox