In the manufacture of oligo arrays for DNA hybridization experiments, manufacturing defects must be detected and their position determined. The design of manufacturing protocols for such oligo arrays leads to a combinatorial problem, requiring certain binary codes which have an additional balance property. Constructions using block designs and packings for these codes, within a range of interest in a practical manufacturing application, are developed. The focus is on equireplicate codes, constant weight codes in which every bit position is a one equally often.
All Science Journal Classification (ASJC) codes
- Binary code
- Block design
- Oligo array