Abstract
Environmental factors play a key role in refining neuronal circuitry in adulthood. Numerous experiences modulate the number of new neurons in the dentate gyrus of the hippocampus, suggesting that adult neurogenesis is an important substrate for experience-dependent change. The influences of stress and the environment on adult neurogenesis, the functional consequences of this process, and its therapeutic potential are discussed in this article.
Original language | English (US) |
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Title of host publication | Encyclopedia of Behavioral Neuroscience, Three-Volume Set, 1-3 |
Publisher | Elsevier |
Pages | V1-485-V1-492 |
Volume | 1 |
ISBN (Electronic) | 9780080453965 |
ISBN (Print) | 9780080914558 |
DOIs | |
State | Published - Jan 1 2010 |
All Science Journal Classification (ASJC) codes
- General Medicine
- General Neuroscience
Keywords
- Adult neurogenesis
- Anxiety
- BrdU
- Depression
- Enriched environment
- Hypothalamic–pituitary–adrenal (HPA) axis
- Learning
- Parenting
- Proliferation
- Social dominance
- Stress
- Voluntary exercise