Enantioselective copper-catalyzed construction of aryl pyrroloindolines via an arylation-cyclization cascade

Research output: Contribution to journalArticle

203 Scopus citations

Abstract

An enantioselective arylation-cyclization cascade has been accomplished using a combination of diaryliodonium salts and asymmetric copper catalysis. These mild catalytic conditions provide a new strategy for the enantioselective construction of pyrroloindolines, an important alkaloid structural motif that is commonly found among biologically active natural products.

Original languageEnglish (US)
Pages (from-to)10815-10818
Number of pages4
JournalJournal of the American Chemical Society
Volume134
Issue number26
DOIs
StatePublished - Jul 4 2012

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

Fingerprint Dive into the research topics of 'Enantioselective copper-catalyzed construction of aryl pyrroloindolines via an arylation-cyclization cascade'. Together they form a unique fingerprint.

  • Cite this