Electroosmotic flows created by surface defects in capillary electrophoresis

Didier Long, Howard A. Stone, Armand Ajdari

Research output: Contribution to journalArticlepeer-review

101 Scopus citations


We compute the electroosmotic flow in nonuniformly charged planar and cylindrical capillaries for the limit of low-Reynolds-number flows and thin Debye layers. Analytical formulae for the velocity field are provided for the general case of an arbitrary surface inhomogeneity but we also focus on various specific defect geometries. Many important features can be obtained from the simple lubrication approximation. The pressure jump induced by the presence of such surface defects is calculated and the possible occurrence of recirculating flows is discussed, as are effects of the flow perturbations on dispersion in capillary electrophoresis.

Original languageEnglish (US)
Pages (from-to)338-349
Number of pages12
JournalJournal of Colloid And Interface Science
Issue number2
StatePublished - Apr 15 1999
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Surfaces, Coatings and Films
  • Biomaterials
  • Colloid and Surface Chemistry


  • Capillary electrophoresis
  • Defects
  • Electroosmotic flow


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