Efficient synthesis of NK1 receptor antagonist aprepitant using a crystallization-induced diastereoselective transformation

Karel M.J. Brands, Joseph F. Payack, Jonathan D. Rosen, Todd D. Nelson, Alexander Candelario, Mark A. Huffman, Matthew M. Zhao, Jing Li, Bridgette Craig, Zhiguo J. Song, David M. Tschaen, Karl Hansen, Paul N. Devine, Philip J. Pye, Kai Rossen, Peter G. Dormer, Robert A. Reamer, Christopher J. Welch, David J. Mathre, Nancy N. TsouJames M. McNamara, Paul J. Reider

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