Efficient synthesis of NK1 receptor antagonist aprepitant using a crystallization-induced diastereoselective transformation

Karel M.J. Brands, Joseph F. Payack, Jonathan D. Rosen, Todd D. Nelson, Alexander Candelario, Mark A. Huffman, Matthew M. Zhao, Jing Li, Bridgette Craig, Zhiguo J. Song, David M. Tschaen, Karl Hansen, Paul N. Devine, Philip J. Pye, Kai Rossen, Peter G. Dormer, Robert A. Reamer, Christopher J. Welch, David J. Mathre, Nancy N. TsouJames M. McNamara, Paul J. Reider

Research output: Contribution to journal › Article › peer-review

161 Scopus citations

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Keyphrases

Pharmacology, Toxicology and Pharmaceutical Science

Biochemistry, Genetics and Molecular Biology

Chemistry