Efficient synthesis of 6-mono-bromo-1,1′-bi-2-naphthol

Dongwei Cai; Robert D. Larsen; Paul J. Reider

doi:10.1016/S0040-4039(02)00730-X

Efficient synthesis of 6-mono-bromo-1,1′-bi-2-naphthol

Dongwei Cai
, Robert D. Larsen
, Paul J. Reider

Research output: Contribution to journal › Article › peer-review

31 Scopus citations

Abstract

Through mono-ester formation of 1,1′-bi-2-naphthol (BINOL) with pivaloyl chloride the selective mono-bromination was achieved cleanly on the other ring to afford 6-mono-bromo-1,1′-bi-2-naphthol in an efficient 86% yield.

Original language	English (US)
Pages (from-to)	4055-4057
Number of pages	3
Journal	Tetrahedron Letters
Volume	43
Issue number	22
DOIs	https://doi.org/10.1016/S0040-4039(02)00730-X
State	Published - May 27 2002
Externally published	Yes

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

Keywords

6-mono-bromo-1,1′-bi-2-naphthol
Bromination

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10.1016/S0040-4039(02)00730-X

Cite this

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title = "Efficient synthesis of 6-mono-bromo-1,1′-bi-2-naphthol",

abstract = "Through mono-ester formation of 1,1′-bi-2-naphthol (BINOL) with pivaloyl chloride the selective mono-bromination was achieved cleanly on the other ring to afford 6-mono-bromo-1,1′-bi-2-naphthol in an efficient 86\% yield.",

keywords = "6-mono-bromo-1,1′-bi-2-naphthol, Bromination",

author = "Dongwei Cai and Larsen, \{Robert D.\} and Reider, \{Paul J.\}",

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doi = "10.1016/S0040-4039(02)00730-X",

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AU - Cai, Dongwei

AU - Larsen, Robert D.

AU - Reider, Paul J.

PY - 2002/5/27

Y1 - 2002/5/27

N2 - Through mono-ester formation of 1,1′-bi-2-naphthol (BINOL) with pivaloyl chloride the selective mono-bromination was achieved cleanly on the other ring to afford 6-mono-bromo-1,1′-bi-2-naphthol in an efficient 86% yield.

AB - Through mono-ester formation of 1,1′-bi-2-naphthol (BINOL) with pivaloyl chloride the selective mono-bromination was achieved cleanly on the other ring to afford 6-mono-bromo-1,1′-bi-2-naphthol in an efficient 86% yield.

KW - 6-mono-bromo-1,1′-bi-2-naphthol

KW - Bromination

UR - https://www.scopus.com/pages/publications/0037182223

UR - https://www.scopus.com/pages/publications/0037182223#tab=citedBy

U2 - 10.1016/S0040-4039(02)00730-X

DO - 10.1016/S0040-4039(02)00730-X

M3 - Article

AN - SCOPUS:0037182223

SN - 0040-4039

VL - 43

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JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 22

ER -

Efficient synthesis of 6-mono-bromo-1,1′-bi-2-naphthol

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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