Dynamics of maternal morphogen gradients in Drosophila

Stanislav Y. Shvartsman, Mathieu Coppey, Alexander M. Berezhkovskii

Research output: Contribution to journalReview articlepeer-review

22 Scopus citations


The first direct studies of morphogen gradients were done in the end of 1980s, in the early Drosophila embryo, which is patterned under the action of four maternally determined morphogens. Since the early studies of maternal morphogens were done with fixed embryos, they were viewed as relatively static signals. Several recent studies analyze dynamics of the anterior, dorsoventral, and terminal patterning signals. The results of these quantitative studies provide critical tests of classical models and reveal new modes of morphogen regulation and readout in one of the most extensively studied patterning systems.

Original languageEnglish (US)
Pages (from-to)342-347
Number of pages6
JournalCurrent Opinion in Genetics and Development
Issue number4
StatePublished - Aug 2008

All Science Journal Classification (ASJC) codes

  • Genetics
  • Developmental Biology


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