Driving force for oxygen-atom transfer by heme-thiolate enzymes

Xiaoshi Wang; Sebastian Peter; René Ullrich; Martin Hofrichter; John Taylor Groves

doi:10.1002/anie.201302137

Driving force for oxygen-atom transfer by heme-thiolate enzymes

Xiaoshi Wang, Sebastian Peter, René Ullrich, Martin Hofrichter, John Taylor Groves

Research output: Contribution to journal › Article › peer-review

47 Scopus citations

Abstract

Absolutely: Redox potentials for three redox couples in AaeAPO-catalyzed reactions have been measured, thus placing these heme-thiolate reactive intermediates on an absolute energy scale for the first time. The importance of the axial thiolate ligand and the basic nature of compoundII ferryl oxygen atom are discussed in terms of these redox potentials.

Original language	English (US)
Pages (from-to)	9238-9241
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	52
Issue number	35
DOIs	https://doi.org/10.1002/anie.201302137
State	Published - Aug 26 2013

All Science Journal Classification (ASJC) codes

General Chemistry
Catalysis

Keywords

cytochromes
kinetics
oxidases
reactive intermediates
redox chemistry

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10.1002/anie.201302137

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abstract = "Absolutely: Redox potentials for three redox couples in AaeAPO-catalyzed reactions have been measured, thus placing these heme-thiolate reactive intermediates on an absolute energy scale for the first time. The importance of the axial thiolate ligand and the basic nature of compoundII ferryl oxygen atom are discussed in terms of these redox potentials.",

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AU - Peter, Sebastian

AU - Ullrich, René

AU - Hofrichter, Martin

AU - Groves, John Taylor

PY - 2013/8/26

Y1 - 2013/8/26

N2 - Absolutely: Redox potentials for three redox couples in AaeAPO-catalyzed reactions have been measured, thus placing these heme-thiolate reactive intermediates on an absolute energy scale for the first time. The importance of the axial thiolate ligand and the basic nature of compoundII ferryl oxygen atom are discussed in terms of these redox potentials.

AB - Absolutely: Redox potentials for three redox couples in AaeAPO-catalyzed reactions have been measured, thus placing these heme-thiolate reactive intermediates on an absolute energy scale for the first time. The importance of the axial thiolate ligand and the basic nature of compoundII ferryl oxygen atom are discussed in terms of these redox potentials.

KW - cytochromes

KW - kinetics

KW - oxidases

KW - reactive intermediates

KW - redox chemistry

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ER -

Driving force for oxygen-atom transfer by heme-thiolate enzymes

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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