DNA-decorated carbon nanotube-based FETs as ultrasensitive chemical sensors: Discrimination of homologues, structural isomers, and optical isomers

S. M. Khamis; R. A. Jones; A. T.C. Johnson; G. Preti; J. Kwak; A. Gelperin

doi:10.1063/1.4705394

DNA-decorated carbon nanotube-based FETs as ultrasensitive chemical sensors: Discrimination of homologues, structural isomers, and optical isomers

S. M. Khamis, R. A. Jones, A. T.C. Johnson, G. Preti, J. Kwak, A. Gelperin

Princeton Neuroscience Institute

Research output: Contribution to journal › Article › peer-review

33 Scopus citations

Abstract

We have explored the abilities of all-electronic DNA-carbon nanotube (DNA-NT) vapor sensors to discriminate very similar classes ofmolecules.We screened hundreds ofDNA-NT devices against a panel of compounds chosen because of their similarities. We demonstrated that DNA-NT vapor sensors readily discriminate between series of chemical homologues that differ by single methyl groups. DNA-NT devices also discriminate among structural isomers and optical isomers, a trait common in biological olfactory systems, but only recently demonstrated for electronic FET based chemical sensors.

Original language	English (US)
Article number	022110
Journal	AIP Advances
Volume	2
Issue number	2
DOIs	https://doi.org/10.1063/1.4705394
State	Published - Jun 2012

All Science Journal Classification (ASJC) codes

General Physics and Astronomy

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10.1063/1.4705394

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title = "DNA-decorated carbon nanotube-based FETs as ultrasensitive chemical sensors: Discrimination of homologues, structural isomers, and optical isomers",

abstract = "We have explored the abilities of all-electronic DNA-carbon nanotube (DNA-NT) vapor sensors to discriminate very similar classes ofmolecules.We screened hundreds ofDNA-NT devices against a panel of compounds chosen because of their similarities. We demonstrated that DNA-NT vapor sensors readily discriminate between series of chemical homologues that differ by single methyl groups. DNA-NT devices also discriminate among structural isomers and optical isomers, a trait common in biological olfactory systems, but only recently demonstrated for electronic FET based chemical sensors.",

author = "Khamis, {S. M.} and Jones, {R. A.} and Johnson, {A. T.C.} and G. Preti and J. Kwak and A. Gelperin",

note = "Funding Information: This work was supported by the Army Research Office through grant # W911NF-11-1-0087 and by the Nano/Bio Interface Center through the National Science Foundation NSEC DMR08-32802.",

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AU - Johnson, A. T.C.

AU - Preti, G.

AU - Kwak, J.

AU - Gelperin, A.

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DNA-decorated carbon nanotube-based FETs as ultrasensitive chemical sensors: Discrimination of homologues, structural isomers, and optical isomers

Abstract

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