DNA-Coated Nanosensors for Breath Analysis

A. T.Charlie Johnson; Samuel M. Khamis; George Preti; Jae Kwak; Alan Gelperin; George Preti; Alan Gelperin

doi:10.1109/JSEN.2009.2035670

DNA-Coated Nanosensors for Breath Analysis

A. T.Charlie Johnson, Samuel M. Khamis, George Preti, Jae Kwak, Alan Gelperin, George Preti, Alan Gelperin

Princeton Neuroscience Institute

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

The analysis of breath and body odors can provide valuable information relevant to disease detection, diagnosis and treatment. A variety of technical developments are being pursued to develop electronic devices intended to analyze volatile components of breath and body odors with the sensitivity, selectivity, and learning ability of high-end mammalian olfactory systems. Here, we describe a new sensor technology that has the potential to supply a large set of diverse and sensitive odorant sensors with electronic readout to provide information-rich odorant-elicited signals for analysis by pattern recognition algorithms. In addition, we demonstrate that these sensors can provide discrimination of odorant homologues consisting of aldehydes and organic acids commonly found in human breath and other body emanations over a range of concentrations.

Original language	English (US)
Pages (from-to)	159-166
Number of pages	8
Journal	IEEE Sensors Journal
Volume	10
Issue number	1
DOIs	https://doi.org/10.1109/JSEN.2009.2035670
State	Published - Jan 2010

All Science Journal Classification (ASJC) codes

Instrumentation
Electrical and Electronic Engineering

Keywords

Breath diagnosis
carbon nanotubes
field effect transistors
human odortypes
odor sensors
pattern recognition
pi-pi stacking

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10.1109/JSEN.2009.2035670

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abstract = "The analysis of breath and body odors can provide valuable information relevant to disease detection, diagnosis and treatment. A variety of technical developments are being pursued to develop electronic devices intended to analyze volatile components of breath and body odors with the sensitivity, selectivity, and learning ability of high-end mammalian olfactory systems. Here, we describe a new sensor technology that has the potential to supply a large set of diverse and sensitive odorant sensors with electronic readout to provide information-rich odorant-elicited signals for analysis by pattern recognition algorithms. In addition, we demonstrate that these sensors can provide discrimination of odorant homologues consisting of aldehydes and organic acids commonly found in human breath and other body emanations over a range of concentrations.",

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AU - Khamis, Samuel M.

AU - Preti, George

AU - Kwak, Jae

AU - Gelperin, Alan

AU - Preti, George

AU - Gelperin, Alan

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DNA-Coated Nanosensors for Breath Analysis

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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