Distribution of telomere-associated sequences in yeast.

V. A. Zakian, H. M. Blanton, L. Wetzel

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Two middle repetitive DNA sequences called X and Y' are found near the telomeres of many chromosomes in Saccharomyces cerevisiae. Orthogonal field gel electrophoresis (OFAGE) was used to examine the distribution of X and Y' on different yeast chromosomes. Although the distribution of X and Y' varies among different laboratory strains of yeast, most yeast chromosomes in four different strains carry both X and Y'. However, at least one chromosome in each strain lacks the Y' element. This result indicates that Y' is not essential for replication or segregation of at least some yeast chromosomes.

Original languageEnglish (US)
Pages (from-to)493-498
Number of pages6
JournalBasic life sciences
Volume40
DOIs
StatePublished - 1986

All Science Journal Classification (ASJC) codes

  • General Medicine

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