Abstract
Immunohistochemical techniques were used to study the distribution of gamma-amino butyric acid (GABA)-like immunoreactive neurons in the nervous system of the slug Limax maximus. Approximately 170 GABA-like immunoreactive cell bodies were found in the central nervous system. These were located in the cerebral, buccal and pedal ganglia. Most GABA-like immunoreactive neurons had small cell bodies, which were aggregated into discrete clusters within the cerebral and pedal ganglia. Three pairs of longer, uniquely identifiable, GABA-like immunoreactive cells were found in the cerebral ganglion. GABA-like immunoreactive nerve fibres were also found in all of the central ganglia but were absent from peripheral nerves. These results suggest that GABA acts as a central neurotransmitter in the slug. The possible roles of GABA-ergic neurotransmission in the slug are discussed.
Original language | English (US) |
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Pages (from-to) | 77-81 |
Number of pages | 5 |
Journal | Cell and Tissue Research |
Volume | 253 |
Issue number | 1 |
DOIs | |
State | Published - Jul 1988 |
All Science Journal Classification (ASJC) codes
- Pathology and Forensic Medicine
- Cell Biology
- Histology
Keywords
- GABA
- Immunohistochemistry
- Limax maximus
- Nervous system
- Neurotransmitter