TY - JOUR
T1 - Directly transmitted viral diseases
T2 - modeling the dynamics of transmission
AU - Lavine, Jennie S.
AU - Poss, Mary
AU - Grenfell, Bryan T.
N1 - Copyright:
Copyright 2019 Elsevier B.V., All rights reserved.
PY - 2008/4
Y1 - 2008/4
N2 - A key hurdle in understanding the spread and control of infectious diseases is to capture appropriately the dynamics of pathogen transmission. As people and goods travel increasingly rapidly around the world, so do pathogens; we must be prepared to understand their spread, in terms of the contact network between hosts, viral life history and within-host dynamics. This will require collaborative work that takes into account viral life history, strategy and evolution, and host genetics, demographics and immunodynamics. Mathematical models are a useful tool for integrating the data and analyses from diverse fields that contribute to our understanding of viral transmission dynamics in heterogeneous host populations.
AB - A key hurdle in understanding the spread and control of infectious diseases is to capture appropriately the dynamics of pathogen transmission. As people and goods travel increasingly rapidly around the world, so do pathogens; we must be prepared to understand their spread, in terms of the contact network between hosts, viral life history and within-host dynamics. This will require collaborative work that takes into account viral life history, strategy and evolution, and host genetics, demographics and immunodynamics. Mathematical models are a useful tool for integrating the data and analyses from diverse fields that contribute to our understanding of viral transmission dynamics in heterogeneous host populations.
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U2 - 10.1016/j.tim.2008.01.007
DO - 10.1016/j.tim.2008.01.007
M3 - Review article
C2 - 18356058
AN - SCOPUS:41549090794
VL - 16
SP - 165
EP - 172
JO - Trends in Microbiology
JF - Trends in Microbiology
SN - 0966-842X
IS - 4
ER -