Abstract
Recently in Science, Huang and co-workers applied directed evolution for the improvement of a non-heme iron oxidase to catalyze the enantioselective radical-relay azidation of N-fluoroamide substrates. They demonstrated the synthetic applicability by using the improved variant in a one-pot, two-step chemoenzymatic synthesis of a highly functionalized triazole product.
Original language | English (US) |
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Pages (from-to) | 2449-2451 |
Number of pages | 3 |
Journal | Chem Catalysis |
Volume | 2 |
Issue number | 10 |
DOIs |
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State | Published - Oct 20 2022 |
Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Chemistry (miscellaneous)
- Physical and Theoretical Chemistry
- Organic Chemistry